CASE REPORT: PONATINIB AS A BRIDGE TO CAR-T CELLS AND SUBSEQUENT MAINTENANCE IN A PATIENT WITH RELAPSED/REFRACTORY PHILADELPHIA-LIKE ACUTE LYMPHOBLASTIC LEUKEMIA

Philadelphia (Ph)-like acute lymphoblastic leukemia (ALL) constitutes a Differential heterogeneous subset of ALL with a uniformly unfavorable prognosis.The identification of mutations amenable to treatment with tyrosine kinase-inhibitors (TKIs) represents a promising field of investigation.We report the case of a young patient affected by relapsed/

The interest in surface treatments promoting dropwise condensation has grown exponentially in the past decades.Savings in the operating and maintenance costs of steam Mouth Protection processes involving phase changes are promised.Numerous surface preparation methods allow the formation of droplets during condensation.However, stable dropwise conde

We describe a gall midge Parampelomyia yukawai Elsayed and Tokuda gen.nov.sp.nov.belonging to the subtribe Schizomyiina (Diptera: Cecidomyiidae: Asphondyliini) based on an integrative taxonomic study.This species forms barely-swollen flower bud galls on the porcelain berry Ampelopsis brevipedunculata var.heterophylla chest strap HR (Vitaceae) in Ja

Economists commonly specialize in some limited parts of the general field.This is a necessity, due to the complexity of the different issues, the amount of literature available on each of them and the possibility of recourse to different analytical or statistical tools.However, specialization has its drawbacks.Quite often, specialists in the fields

Objectives: The pig is a common model utilized to support substantiation of novel bioactive components in infant formula.However, reference ranges for outcomes to determine safety are unclear.Our objective was to use historical data to objectively define typical body and organ growth metrics of the domesticated pig in research.Methods: Twenty-two s